Audio format can be tricky, Safari likes Ogg Vorbis, Firefox doesn't like WAV, etc... I found an Ogg & a MP3 will get you far. As far as players go, I found a JS program that opens a small window for the player. I wanted people to be able to continue looking around while still listening to the podcast, but not have a another full-size window open up.
I found podcasts sounded better if I was actually interviewing someone, as opposed to supplying the impressions myself and editing later. I have some talented friends who were more than willing to offer some time and their talents to make this podcast happen.
Once the character was settled, we would pick a topic, and just talk about it until it ran dry. Then we would do it again and sometimes a third. Afterwards, I would use some editing software to splice all the good stuff together.